The Broncos thrashed the Tigers 46-12 on the back of masterclasses from Reece Walsh, Adam Reynolds and Payne Haas in the battle between first and last at Suncorp Stadium.
The Broncos have now won their first five games of the season for the first time since 1998 when they beat the Bulldogs in the grand final to lift the trophy.
MATCH CENTRE: Brisbane Broncos vs Wests Tigers teams, scores, stats, videos