NRL stars Dom Young, Victor Radley, Elliott Whitehead, Tom Burgess and John Bateman headline a 24-man England squad for the historic Test series against Tonga.
However, Broncos centre Herbie Farnworth is among a number of players ruled out with injury, while former Raiders halfback George Williams - the England captain - is suspended.
Williams received a two match ban for a shoulder charge in Warrington's finals loss to St Helens but the extent of his involvement in the three Test series could be determined at an appeal hearing on Tuesday night.
