Canberra has scored an upset 20-14 victory over Brisbane at Lang Park to end the competition leader's unbeaten start to the season.
In Saturday's earlier match, Penrith embarrassed Manly in a 44-12 demolition, with Panthers fullback Dylan Edwards crossing for four tries.
The Raiders were hammered 53-12 the previous week by Penrith but were a different team from the start against the Broncos.
This was despite the fact they were without suspended five-eighth Jack Wighton and inspirational prop Joe Tapine, who stayed home awaiting the arrival of his first child.